Symbol
Name
ID

Gria4
glutamate receptor, ionotropic, AMPA4 (alpha 4)
MGI:95811

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	EEG abnormality	Delusion	Schizophrenia	Hallucinations	Negativism	Social and occupational deterioration
Disease(s) Associated with GRIA4
schizophrenia

Mouse Phenotypes

nervous system phenotype

abnormal seizure response to pharmacological agent

absence seizures

abnormal spike wave discharge

abnormal nervous system electrophysiology

abnormal action potential

impaired ability to fire action potentials

abnormal neuron physiology

abnormal excitatory postsynaptic potential

abnormal glutamate-mediated receptor currents

abnormal AMPA-mediated synaptic currents

abnormal inhibitory postsynaptic potential

decreased prepulse inhibition

Availability

Mouse Genotype

Gria4^spkw1/Gria4^spkw1

Gria4^tm1.1Mony/Gria4^tm1.1Mony

Gria4^tm1Dgen/Gria4^tm1Dgen

Gria4^tm1Rlh/Gria4^tm1Rlh

Gria4^tm1Yfkk/Gria4^tm1Yfkk

Gria4^spkw1/Gria4⁺

Gria4^spkw1/Gria4^tm1Dgen

Gria4^tm1Dgen/Gria4⁺

Gja10^{tm2.1(cre)Kwi}/Gja10⁺
Gria4^tm1Mony/Gria4^tm1Mony (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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